Clinical trials
The Division of Surgery is engaged in a broad range of clinical trials, with far-reaching translational benefits and implications for patients. Explore the categories below to find out more about each of our clinical trials:
Clinical trials list
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B
- Behaviour
- Health messages to Improve the Participation in Cervical and Breast Cancer Screening
- Redesigned letter invitations to improve the participation in Cervical Cancer Screening
- SMS Reminders to Improve the Participation in Breast Screening
- SMS Reminders to Improve the Participation in Cervical Cancer Screening
- Breast Cancer
- Behaviour
-
C
- Colorectal Cancer
- COLOR III trial – Multicentre randomised clinical trial comparing transanal versus traditional laparoscopic total mesorectal excision for mid and low rectal cancer
- European Commission PICCOLO Multimodal highly-sensitive PhotonICs endoscope for improved in-vivo COLOn Cancer diagnosis €6,000,000. A European collaboration to develop an endoscope with optical biopsy capability
- Evaluating the role of Neurotensin (NT) as a diagnostic marker for colonic polyps and colorectal cancers
- Evaluation of Quality of Life (QOL) and Cost Effectiveness of Pelvic Exenterative Surgery (Beyond TME) for Primary Locally Advanced and Recurrent Colorectal Cancer from a Dedicated Multidisciplinary Colorectal Cancer Centre
- Imperial/Royal Marsden joint BRC award - the role of the microbiome in the development and progression of colorectal cancer
- Metabolic biomarkers for Early Colon cancer and advanced AdeNOma Study (MECANO)
- MetabOlomics-based patient StrAtification for guiding multI-modality therapy in Colorectal cancer (MOSAIC study)
- Rapid evaporative ionisation mass spectrometry (REISM) for the analysis of cancer resection margins in locally advanced and recurrent rectal cancer
- The role of Neurotensin (NT) and its receptors (NTSR1) in the endoscopic screening of high-risk population for developing colorectal neoplasia
- Tracking mutations in cell-free tumour DNA to predict Relapse in early Colorectal Cancer (TRACC study)
- Colorectal Cancer
-
O
- Obesity, Diabetes and Bariatric Surgery
- A randomized controlled trial of a duodenal sleeve bypass device (Endobarrier) compared with standard medical therapy for the management of obese subjects with type 2 diabetes (Co-I)
- Are gut hormone changes why the long-limb gastric bypass is more effective than the standard-limb gastric bypass in improving type 2 diabetes mellitus?
- Are the metabolic and weight loss effects of Roux-en-Y bypass surgery mediated by gut hormones?
- ByBandSleeve - Imperial NIHR Health Technology Assessment Programme
- Controlled trial of a duodenal sleeve bypass device (Endobarrier) compared with standard medical therapy for the management of obese subjects with type 2 diabetes
- Longitudinal Phenotyping of Bariatric Surgery Patients
- Multicentre Reload study
- Personalised Medicine for Morbid Obesity (PMMO)
- SLR prospective case series review
- Organisational Health and Healthcare Organisations
- A longitudinal, observational study of organisational health within a single UK NHS trust
- Organisational health and acute NHS trusts
- Organisational health and non-UK health organisations
- Organisational health and the independent health sector
- Organisational health and the primary care sector
- Obesity, Diabetes and Bariatric Surgery
-
P
- Perioperative Care
- PREPARE- Prehabilitation in patients undergoing oesophagogastric cancer surgery
- PROMPT- a health foundation funded project on peri-operative remote monitoring of patients
- Perioperative Care
-
U
- Upper Gastrointestinal Cancer
- NEO-AEGIS study which is a multicentre phase III open-labelled, randomised controlled trial
- OCCAMS (Oesophageal Cancer Clinical and Molecular Stratification) study
- POEM (Predicting Outcome in Esophageal Malignancy)
- Urology
- Upper Gastrointestinal Cancer
-
V
- Vascular
- AARDVARK - Evaluating the role of ACE inhibitors to slow the growth of aneurysm
- ANCHOR registry, Observation study of a novel fixation device for aortic stent grafts to prevent migration
- CHAPS - Compression Hosiery to Avoid Post-Thrombotic Syndrome
- Compression following endovenous treatment of varicose veins using foam sclerotherapy
- Compression Therapy following Endothermal Ablation
- DAVE - Decellularised Dermis Allograft for the Treatment of Chronic Venous Leg Ulceration
- DETECT - Detection of EVAR sac expansion using ultrasound surveillance
- Does Neuromuscular Electrical Stimulation Improve the Absolute Walking Distance in Patients with Intermittent Claudication (NESIC) compared to best available treatment?
- DM PAD - Diagnostic tools to establish the presence and severity of peripheral arterial disease in people with diabetes
- EndoVascular Aneurysm Repair Trials (EVAR)
- Early Venous Reflux Ablation Ulcer Trial (EVRA)
- Graduated compression as an Adjunct to Pharmacoprophylaxis in Surgery (GAPS)
- Incentives in Diabetic Eye Assessment by Screening Trial (IDEAS)
- Immediate Management of Patients with Ruptured Aneurysm: Open Versus Endovascular Repair (IMPROVE)
- Late aneurysm-related mortality up to 15 years, secondary endovascular repair, late sac rupture risk, costs & cost effectiveness implications in the United Kingdom EndoVascular Aneurysm Repair randomised controlled trials and management of type II endoleaks
- MEASURE AAA
- Metabolic Biomarker Responses in Acute Cerebral Events (MBRACE)
- Metabolic profiling in a murine DVT model
- Metabolic profiling of chronic venous ulceration
- Metabolic profiling of venous disease
- Metaboplasty
- Pilot study evaluating a One Stop Vein Clinic
- Population studies in vascular disease
- Valiant EVO trial, Assessment of a new thoracic endovascular stent graft system
- AARDVARK - Evaluating the role of ACE inhibitors to slow the growth of aneurysm
- Vascular