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• Journal article
  Koenig SLB, Liyanage PS, Sigel RKO, Rueda Det al., 2013,

  Helicase-mediated changes in RNA structure at the single-molecule level

  , RNA BIOLOGY, Vol: 10, Pages: 133-148, ISSN: 1547-6286
  • Cite
  • Citations: 15
• Journal article
  Cauldwell AV, Moncorge O, Barclay WS, 2013,

  Unstable Polymerase-Nucleoprotein Interaction Is Not Responsible for Avian Influenza Virus Polymerase Restriction in Human Cells

  , JOURNAL OF VIROLOGY, Vol: 87, Pages: 1278-1284, ISSN: 0022-538X
  • Cite
  • Citations: 37
• Journal article
  Moncorge O, Long JS, Cauldwell AV, Zhou H, Lycett SJ, Barclay WSet al., 2013,

  Investigation of Influenza Virus Polymerase Activity in Pig Cells

  , JOURNAL OF VIROLOGY, Vol: 87, Pages: 384-394, ISSN: 0022-538X
  • Author Web Link
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  • Citations: 44
• Journal article
  Tzellos S, Farrell PJ, 2012,

  Epstein-barr virus sequence variation-biology and disease.

  , Pathogens, Vol: 1, Pages: 156-174, ISSN: 2076-0817

  Some key questions in Epstein-Barr virus (EBV) biology center on whether naturally occurring sequence differences in the virus affect infection or EBV associated diseases. Understanding the pattern of EBV sequence variation is also important for possible development of EBV vaccines. At present EBV isolates worldwide can be grouped into Type 1 and Type 2, a classification based on the EBNA2 gene sequence. Type 1 EBV is the most prevalent worldwide but Type 2 is common in parts of Africa. Type 1 transforms human B cells into lymphoblastoid cell lines much more efficiently than Type 2 EBV. Molecular mechanisms that may account for this difference in cell transformation are now becoming clearer. Advances in sequencing technology will greatly increase the amount of whole EBV genome data for EBV isolated from different parts of the world. Study of regional variation of EBV strains independent of the Type 1/Type 2 classification and systematic investigation of the relationship between viral strains, infection and disease will become possible. The recent discovery that specific mutation of the EBV EBNA3B gene may be linked to development of diffuse large B cell lymphoma illustrates the importance that mutations in the virus genome may have in infection and human disease.

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• Journal article
  Sridhar S, Begom S, Bermingham A, Ziegler T, Roberts KL, Barclay WS, Openshaw P, Lalvani Aet al., 2012,

  Predominance of heterosubtypic IFN-?-only-secreting effector memory T cells in pandemic H1N1 naive adults

  , EUROPEAN JOURNAL OF IMMUNOLOGY, Vol: 42, Pages: 2913-2924, ISSN: 0014-2980
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  • Citations: 28
• Journal article
  Hatzimichael E, Lo Nigro C, Lattanzio L, Syed N, Shah R, Dasoula A, Janczar K, Vivenza D, Monteverde M, Merlano M, Papoudou-Bai A, Bai M, Schmid P, Stebbing J, Bower M, Dyer MJS, Karran LE, ElguetaKarstegl C, Farrell PJ, Thompson A, Briasoulis E, Crook Tet al., 2012,

  The collagen prolyl hydroxylases are novel transcriptionally silenced genes in lymphoma

  , British Journal of Cancer, Vol: 107, Pages: 1423-1432, ISSN: 1532-1827
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• Journal article
  Roberts KL, Shelton H, Stilwell P, Barclay WSet al., 2012,

  Transmission of a 2009 H1N1 Pandemic Influenza Virus Occurs before Fever Is Detected, in the Ferret Model

  , PLOS ONE, Vol: 7, ISSN: 1932-6203
  • Cite
  • Citations: 38
• Journal article
  Paschos K, Parker GA, Watanatanasup E, White RE, Allday MJet al., 2012,

  BIM promoter directly targeted by EBNA3C in polycomb-mediated repression by EBV

  , NUCLEIC ACIDS RESEARCH, Vol: 40, Pages: 7233-7246, ISSN: 0305-1048
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  • Citations: 96
• Journal article
  Kwok H, Tong AHY, Lin CH, Lok S, Farrell PJ, Kwong DLW, Chiang AKSet al., 2012,

  Genomic Sequencing and Comparative Analysis of Epstein-Barr Virus Genome Isolated from Primary Nasopharyngeal Carcinoma Biopsy

  , PLOS ONE, Vol: 7, ISSN: 1932-6203
  • Author Web Link
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  • Citations: 75
• Journal article
  Buettner M, Lang A, Tudor CS, Meyer B, Cruchley A, Barros MHM, Farrell PJ, Jaeck H-M, Schuh W, Niedobitek Get al., 2012,

  Lytic Epstein-Barr virus infection in epithelial cells but not in B-lymphocytes is dependent on Blimp1

  , JOURNAL OF GENERAL VIROLOGY, Vol: 93, Pages: 1059-1064, ISSN: 0022-1317
  • Author Web Link
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  • Citations: 19

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