Metabolic Medicine
The Section of Metabolic Medicine focusses on clinical diabetes research. The Section has developed an international reputation in health technology development and assessment, and is applying this to support people living with diabetes to self manage more effectively.
Research themes include closed-loop insulin delivery, novel small molecule sensing and personalised decision support using case based reasoning. The active technology research programmes are cross-faculty and multidisciplinary, incorporating expertise from the Faculty of Engineering and Faculty of Natural Sciences.
Imperial is the co-ordinating centre for the diabetes theme of the NIHR Clinical Research Network, and leads the ADDRESS-2 study of new onset type 1 diabetes.
We have partnered with Oxford Brookes University, Universitat de Girona, Institut d'Investigació Biomèdica de Girona, Romsoft and cellnovo to bring together computer scientists, clinicians and industry leaders to create a personalised decision support system for diabetes management – the PEPPER project.
In addition to working toward revolutionising diabetes self management we are harnessing technology to address the growing challenges of diabetes diagnosis in a young, multi-ethnic population using a combination of genomic, biochemical and clinical parameters to ensure people with new onset diabetes receive the appropriate treatment – the MY DIABETES Study. This work is in collaboration with NIHR Imperial BRC Genomics Facility.
The Section is also addressing the growing prevalence of type 2 diabetes with diabetes prevention studies using text messaging technology and pharmacology, and contributes to both undergraduate and postgraduate medical education within the Faculty of Medicine.
Research
Studies
ADDRESS-2 study - learning about the characteristics of people newly diagnosed with type 1 with diabetes in the UK and supporting other research into type 1 diabetes.
ABC4D study - Advanced Bolus Calculator for Diabetes.
BiAP study - Clinical Evaluation of an Artificial Pancreas in people with Type 1 Diabetes. Publication found here.
I HART CGM study - Comparison of Continuous Glucose Monitoring vs. Flash Glucose Monitoring in Type 1 diabetes. Publication found here.
PEPPER study - Personalised Decision Support system for diabetes management in Type 1 Diabetes.
MY DIABETES study - Characterising Young-Onset Diabetes in two UK ethnic groups, specifically identifying potential genetic causes to their diabetes known as Maturity Onset Diabetes of the Young (MODY).
WynnMet - The Wynn Database: Metabolic Risk Factors and Mortality
Other Research Areas
- Using intelligent systems e.g. health apps to support Type 1 Diabetes
- Using mobile technology to promote lifestyle changes to prevent Type 2 diabetes
- Cardiovascular risk
- Complications of pregnancy
- Type 2 diabetes
Head of Metabolic Medicine
Professor Desmond Johnston leads a team of researchers investigating early changes in insulin secretion and insulin sensitivity, and other aspects of metabolism in people predisposed to Type 2 diabetes before diabetes develops. He is also interested in the mechanisms underlying the premature vascular disease to which people with diabetes are prone and in the associated metabolic disturbances such as non-alcoholic fatty liver disease. He has published hundreds of research papers on this and other related areas.
Research Team
Dr Rochan Agha-Jaffar
/dev01/channel_2/media/migration/faculty-of-medicine/silhouette--t_1430232718181_x2--t_1458213756113_x2--tojpeg_1532954634384_x4.jpg)
Dr Rochan Agha-Jaffar
Dr Parizad Avari
/dev01/channel_2/media/migration/faculty-of-medicine/silhouette--t_1430232718181_x2--t_1458213756113_x2--tojpeg_1532439592803_x4.jpg)
Dr Parizad Avari
Mrs Heather Bones
/dev01/channel_2/media/migration/faculty-of-medicine/H-BONES--tojpeg_1532441111459_x4.jpg)
Mrs Heather Bones
Dr Ian Godsland
/dev01/channel_2/media/migration/faculty-of-medicine/Ian-Godsland--tojpeg_1458305158294_x4.jpg)
Dr Ian Godsland
Dr Neil Hill
/dev01/channel_2/media/migration/faculty-of-medicine/silhouette--t_1430232718181_x2--t_1458213756113_x2--tojpeg_1532439411902_x4.jpg)
Dr Neil Hill
Prof Desmond Johnston
/dev01/channel_2/media/migration/faculty-of-medicine/Professor-Desmond-Johnston--tojpeg_1458305351992_x4.jpg)
Prof Desmond Johnston
Ms Narvada Jugnee
/dev01/channel_2/media/migration/faculty-of-medicine/silhouette--t_1430232718181_x2--t_1458213756113_x2--tojpeg_1532440525236_x4.jpg)
Ms Narvada Jugnee
Ms Akaal Kaur
/dev01/channel_2/media/migration/faculty-of-medicine/silhouette--t_1430232718181_x2--t_1458213756113_x2--tojpeg_1532440257085_x4.jpg)
Ms Akaal Kaur
Dr Shivani Misra
/dev01/channel_2/media/migration/faculty-of-medicine/S-MISRA-resized--tojpeg_1532438740628_x4.jpg)
Dr Shivani Misra
Ms Kanchana Ngaosuwan
/dev01/channel_2/media/migration/faculty-of-medicine/silhouette--t_1430232718181_x2--t_1458213756113_x2--tojpeg_1532440995024_x4.jpg)
Ms Kanchana Ngaosuwan
Prof Nick Oliver
/dev01/channel_2/media/migration/faculty-of-medicine/Nick-Oliver--tojpeg_1458305065509_x4.jpg)
Prof Nick Oliver
Dr Monika Reddy
/dev01/channel_2/media/migration/faculty-of-medicine/silhouette--t_1430232718181_x2--t_1458213756113_x2--tojpeg_1532438986330_x4.jpg)
Dr Monika Reddy
Miss Sian Rilstone
/dev01/channel_2/media/migration/faculty-of-medicine/silhouette--t_1430232718181_x2--t_1458213756113_x2--tojpeg_1532439505817_x4.jpg)
Miss Sian Rilstone
Mr Weerachai Srivanichakorn
/dev01/channel_2/media/migration/faculty-of-medicine/silhouette--t_1430232718181_x2--t_1458213756113_x2--tojpeg_1532440897227_x4.jpg)
Mr Weerachai Srivanichakorn
Ms Maria Thomas
/dev01/channel_2/media/migration/faculty-of-medicine/silhouette--t_1430232718181_x2--t_1458213756113_x2--tojpeg_1532441168267_x4.jpg)
Ms Maria Thomas
Ms Hazel Thomson
/dev01/channel_2/media/migration/faculty-of-medicine/silhouette--t_1430232718181_x2--t_1458213756113_x2--tojpeg_1532440721671_x4.jpg)
Ms Hazel Thomson
Dr Chukwuma Uduku
/dev01/channel_2/media/migration/faculty-of-medicine/silhouette--t_1430232718181_x2--t_1458213756113_x2--tojpeg_1532439756187_x4.jpg)
Dr Chukwuma Uduku
Dr Helen Walkey
/dev01/channel_2/media/migration/faculty-of-medicine/silhouette--t_1430232718181_x2--t_1458213756113_x2--tojpeg_1532440014170_x4.jpg)
Dr Helen Walkey
Privacy
Privacy Statement
You can view our privacy statement here: