MicroSleepStage Platform

BLV2.1 platform showing:4-channel ECoG/EMG logging device (left);Android App for device control and real time data visualization (centre);Example 10-h recording data analysed in Spike2.
BLV2.1 platform showing:4-channel ECoG/EMG logging device (left);Android App for device control and real time data visualization (centre);Example 10-h recording data analysed in Spike2.

Overview

BLV2.1 and BLV3.0 are neural recording ( ECoG/EMG ) devices designed to help researchers working in neuroscience and especially in the sleep study field. Their compact and light weight design, as well as a long battery life, make them ideal in sleep studies that involve small rodents such as mice.  Whilst BLV2.1 supports only ( ECoG/EMG ) recording. BLV3.0 on the other hand, is a closed loop device that has integrated neural recording, temperature measurement, on line sleep-stage scoring and optogenetic stimulation all into one platform.

Features

  • 4-channel ECoG and EMG recording/streaming at 200Hz
  • Compact ( 17mm by 19mm ) for BLV2.1 and ( 15mm by 15mm ) for BLV3.0
  • Light weight, ( 3.1g ) for BLV2.1 and (2.2g) for BLV3.0
  • Long recording life ( <4 days ) for BLV2.1 and ( <2 days ) for BLV3.0
  • Cortical and core temperature recording via a T type thermocouple
  • Real-time sleep stage (Wake, NREM, REM) scoring
  • Optogenetic stimulation ( up to 30mW ) with fully configurable parameters
  • Fast data download via a custom interface board
  • Fully controllable via a custom Android App

Applications

  • ECoG/EMG signal acquisition systems for neuroscience
  • Open-loop behavioural studies via optogenetic stimulation
  • Closed-loop sleep studies via on-line sleep stage scoring algorithm and optogenetic stimulation
  • Sleep studies in rodents
  • Cortical and core thermoregulation during sleep

Top and Bottom views of BLV3.0 (left) and BLV2.1(right).
Top and Bottom views of BLV3.0 (left) and BLV2.1(right).

Publications

Hsieh B, Harding E, Wisden W, et al.A miniature neural recording device to investigate sleep and temperature regulation in mice, IEEE Biomedical Circuits and Systems (BioCAS) Conference, IEEE