@article{Liu:2026:jcag/gwaf042.036,
author = {Liu, CS and Merrick, B and Taboun, Z and Mullish, B and Kuijper, E and Kao, D},
doi = {jcag/gwaf042.036},
journal = {Journal of the Canadian Association of Gastroenterology},
title = {Poster Session I - A36 OPTIMIZING AND STANDARDIZING DONOR SCREENING FOR FECAL MICROBIOTA TRANSPLANTATION: A DELPHI REVIEW},
url = {http://dx.doi.org/10.1093/jcag/gwaf042.036},
volume = {9},
year = {2026}
}

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TY  - JOUR
AB  - <jats:title>Abstract</jats:title>                  <jats:sec>                    <jats:title>Background</jats:title>                    <jats:p>Fecal microbiota transplantation (FMT) transfers stool from healthy donors to recipients and is highly effective for preventing recurrent Clostridioides difficile infection. However, rare cases of FMT-associated infections have resulted in morbidity and even mortality. Despite the critical importance of screening, evidence-based approaches to developing donor-screening protocols remain limited.</jats:p>                  </jats:sec>                  <jats:sec>                    <jats:title>Aims</jats:title>                    <jats:p>This review aimed to evaluate the evidence underpinning current FMT donor screening protocols by critically appraising existing literature on pathogen transmission dynamics.</jats:p>                  </jats:sec>                  <jats:sec>                    <jats:title>Methods</jats:title>                    <jats:p>We conducted a comprehensive review up to November 2024. Key factors considered included the geographical distribution of pathogens, likelihood of fecal-oral transmission via FMT, and the clinical consequences of potential transmission events. A Delphi process involving 25 experts in stool banking, donor screening, and FMT preparation and administration was undertaken to establish consensus on the transmissibility of pathogens via FMT, defined as ≥ 80% agreement. Transmission was categorized as definite when supported by documented evidence (e.g., case reports or confirmed donor-to-recipient transmission), possible when fecal-oral transmission was plausible but unconfirmed, and not possible when such transmission was considered unlikely.</jats:p>                  </jats:sec>                  <jats:sec>                    <jats:title>Res
AU  - Liu,CS
AU  - Merrick,B
AU  - Taboun,Z
AU  - Mullish,B
AU  - Kuijper,E
AU  - Kao,D
DO  - jcag/gwaf042.036
PY  - 2026///
SN  - 2515-2084
TI  - Poster Session I - A36 OPTIMIZING AND STANDARDIZING DONOR SCREENING FOR FECAL MICROBIOTA TRANSPLANTATION: A DELPHI REVIEW
T2  - Journal of the Canadian Association of Gastroenterology
UR  - http://dx.doi.org/10.1093/jcag/gwaf042.036
UR  - https://doi.org/10.1093/jcag/gwaf042.036
VL  - 9
ER  - 

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