@article{Mohammadi:2026:10.1016/j.jnoncrysol.2026.124322,
author = {Mohammadi, SS and Phull, SS and Law, RV and Towler, MR},
doi = {10.1016/j.jnoncrysol.2026.124322},
journal = {Journal of Non Crystalline Solids},
title = {Effect of SrO doping on network structure and degradation behaviour of alkali-free borate bioactive glass},
url = {http://dx.doi.org/10.1016/j.jnoncrysol.2026.124322},
volume = {691},
year = {2026}
}

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TY  - JOUR
AB  - Borate-based glasses are attractive for bone regeneration due to their rapid dissolution and their ability to promote the formation of an apatite-like layer in physiological environments. However, a challenge associated with borate glasses is controlling boron ion (B) release, which is critical for maintaining biocompatibility and structural stability. In this study, a borate glass series based on 47B<inf>2</inf>O<inf>3</inf>-XSrO-17ZnO-11Ag<inf>2</inf>O-(25-X)CaO (wt%, X = 0, 1, 3, and 5) glasses were synthesized to investigate the influence of strontium oxide (SrO) on glass structure, thermal behaviour, and B release. X-ray diffraction (XRD) confirmed that all compositions were fully amorphous, and <sup>11</sup>B magic angle spinning nuclear magnetic resonance (MAS-NMR) revealed no significant changes in B speciation with SrO incorporation. Differential scanning calorimetry (DSC) showed a progressive decrease in melting temperature with increasing SrO content, suggesting that SrO modifies the melt behavior of the borate glass system. However, the relatively constant T<inf>g</inf> and T<inf>c</inf> values across compositions indicate that overall thermal stability and network rigidity were not substantially altered. Immersion in phosphate-buffered saline for up to 60 days demonstrated that B release increased with immersion time, while only the highest SrO substitution (5 wt%) showed a statistically significant difference compared with the Sr-free control. These findings suggest that, within alkali-free borate glass systems, SrO acts as a secondary network modifier that modestly influences long-term B dissolution without substantially altering early-stage degradation behavior.
AU  - Mohammadi,SS
AU  - Phull,SS
AU  - Law,RV
AU  - Towler,MR
DO  - 10.1016/j.jnoncrysol.2026.124322
PY  - 2026///
SN  - 0022-3093
TI  - Effect of SrO doping on network structure and degradation behaviour of alkali-free borate bioactive glass
T2  - Journal of Non Crystalline Solids
UR  - http://dx.doi.org/10.1016/j.jnoncrysol.2026.124322
VL  - 691
ER  - 

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