Join the team!

We have a PhD position open in our laboratory

Deadline for applications: Sunday, September 17, 2023 

We invite applications for a PhD position in our laboratory to work on an exciting project exploring the role of TGFb in the regulation of Haematopoietic Stem Cells (HSC) quiescence and proliferation

Every day our body generates billions of blood cells. This process relies on a rare population of haematopoietic stem cells (HSC), that reside in specialized niches in bone marrow. Research in our laboratory focuses on understanding how the bone marrow microenvironment regulates HSC function in the maintenance of blood cells homeostasis, blood cells regeneration, aging, and the development of haematological malignancies. You will work on an exciting project aimed at understanding the molecular mechanisms by which bone marrow TGFb regulates HSCs quiescence and proliferation, in response to different situations of perturbed haematopoiesis. We will identify new regulators involved in this process and functionally investigate them, using mouse models of perturbed haematopoiesis. This is a multidisciplinary project involving the use of different transgenic mouse models, which will be analyzed with in vivo assays, cutting edge multi-parameter flow cytometry, confocal microscopy of the bone marrow niche and gene expression techniques (including multiplex qPCR and RNA sequencing)

Candidates are encouraged to contact Dr Tiago Luis to discuss their application. Get in Touch! 

How to apply:

Applicants are requested to send a full CV (including the names and email addresses of two academic referees), and personal statement detailing why you are interested in the research project (maximum 1 side A4, font size 12 Arial) to Ed Wallace (e.wallace@imperial.ac.uk). The successful candidate will be asked to complete an electronic application form at Imperial College London to allow their qualifications to be reviewed by College Registry.

Requirements and Eligibility

Applicants should have a Master’s degree in Bio-medical Sciences or equivalent experience working in a laboratory. Previous experience with transgenic mouse models, flow cytometry, confocal microscopy and/or Bioinformatics skills using R will be considered an asset. 

Applicants are also required to meet Imperial College’s requirements regarding academic qualifications and English language to register for a PhD.

Funding notes:

Stipend: £20,622 (inclusive of London allowance) per annum + Tuition Fees (Home) for 3 years. A consumables budget is also provided.

This is a fully funded PhD position, including a tax-free stipend and Home fees and consumables for 3 years. Qualification for Home fees is only available to UK citizens or those who have been resident in the UK for a period of 3 years or more. More detail is provided in UKCISA's guide: View Website. Non-Home students are welcome to apply, but should be able to demonstrate adequate financial support to cover the difference between the Home fee and the Non-Home fee.

We also welcome informal inquires about other opportunities to join the lab.

We welcome researchers from all over the world.  If you need to apply for a Visa, our Human Resources team will provide all the support needed to guide you through the process.