We use perceptual methods, AI, and frugal robotics innovation to deliver transformative diagnostic and treatment solutions.
B415B Bessemer Building
South Kensington Campus
+44 (0)20 3312 5145
The HARMS lab leverages perceptually enabled methodologies, artificial intelligence, and frugal innovation in robotics (such as soft surgical robots) to deliver transformative solutions for diagnosis and treatment. Our research is driven by both problem-solving and curiosity, aiming to build a comprehensive understanding of the actions, interactions, and reactions occurring in the operating room. We focus on using robotic technologies to facilitate procedures that are not yet widely adopted, particularly in endoluminal surgery, such as advanced treatments for gastrointestinal cancer.
Mr Amirhosein Alian
Casual - Other work
Dr Said Alyacoubi
Clinical Research Fellows
Dr James P Avery
Honorary Lecturer
Mr Junhong Chen
Casual
Mr Kaizhong Deng
Research Postgraduate
Mr KAIZHE JIN
Research Postgraduate
Mr Hanqi LOU
Research Postgraduate
Dr George Mylonas BEng, MSc, DIC, PhD
Associate Professor in Robotics and Technology in Cancer
Dr Adrian Rubio Solis
Research Associate in Sensing and Machine Learning
Dr Jianlin Yang
Research Associate
Mr Zhangxi Zhou
Research Postgraduate
@article{Avila-Rencoret:2023:10.1002/tbio.202200013,
author = {Avila-Rencoret, F and Mylonas, G and Elson, D},
doi = {10.1002/tbio.202200013},
journal = {Translational Biophotonics},
title = {Robotic large-area optical biopsy imaging for automated detection of gastrointestinal cancers tested in tissue phantoms and ex vivo porcine bowel},
url = {http://dx.doi.org/10.1002/tbio.202200013},
volume = {5},
year = {2023}
}
TY - JOUR
AB - Gastrointestinal endoscopy is a subjective procedure that frequently requires tissue samples for diagnosis. Contact optical biopsy (OB) techniques have the aim of providing direct diagnosis of endoscopic areas without excising tissue samples but lack the wide-area coverage required for locating and resecting lesions. This article presents a large-area robotically deployed OB imaging platform for endoscopic detection of colorectal cancer as an add-on for conventional endoscopes. In vitro, in silicon colon phantoms, the platform achieves an optical resolution of 0.5 line pairs per millimeter, while resolving simulated cancer lesions down to 0.75 mm diameter across large-area images (55-103 cm2). Large-area OB images were generated in an ex vivo porcine colon. The platform allows centimeter-sized large-area OB imaging in vitro and ex vivo with submillimeter resolution, including automatic data segmentation of simulated cancer areas. The ability for robotic actuation and spectrum collection is also shown for ex vivo animal colon. If successful, this technology could widen access to user-independent high-quality endoscopy and early detection of gastrointestinal cancers.
AU - Avila-Rencoret,F
AU - Mylonas,G
AU - Elson,D
DO - 10.1002/tbio.202200013
PY - 2023///
SN - 2627-1850
TI - Robotic large-area optical biopsy imaging for automated detection of gastrointestinal cancers tested in tissue phantoms and ex vivo porcine bowel
T2 - Translational Biophotonics
UR - http://dx.doi.org/10.1002/tbio.202200013
VL - 5
ER -